JAM Lecture 2013: Professor Peter Setlow

When the Sleepers Wake: The Germination of Bacterial Spores

Dr. Setlow’s research over the past ~40 years has focused on spore formers of various Bacillus species, concentrating on the mechanisms of the formation, resistance, killing and germination of the spores of these organisms, as well as their biochemical properties, and he has published over 400 research papers on these topics. This work has utilized techniques from many disciplines including: 1) microbial physiology; 2) molecular genetics; 3) molecular biology; 4) classical genetics; 5) light and fluorescence microscopy; 6) enzyme purification and characterization; 7) spectroscopy of single cells; 8) small molecule analysis; and 9) structural biology.